Pasqua, Oscar Della: search on Z-Library

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1

Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling: Biophase Distribution, Receptor Theory, and Dynamical Systems Analysis

Danhof, Meindert, de Jongh, Joost, De Lange, Elizabeth C.M., Della Pasqua, Oscar, Ploeger, Bart A., Voskuyl, Rob A.

Journal:

Annual Review of Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.26 MB

english, 2007

2

Modelâbased metaâanalysis of individual IPSS trajectories in patients with benign prostatic hyperplasia with moderate or severe symptoms

D'Agate, Salvatore, Wilson, Timothy, Adalig, Burkay, Manyak, Michael, PalaciosâMoreno, Juan Manuel, Chavan, Chandrashekhar, Oelke, Matthias, Roehrborn, Claus, Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2020

File:

PDF, 2.53 MB

2020

3

Population pharmacokinetics of carvedilol enantiomers and their metabolites in type-2 diabetes and healthy subjects

Nardotto, Glauco H.B., Lanchote, Vera L., Coelho, Eduardo B., Della Pasqua, Oscar

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.63 MB

english, 2017

4

Identifying the translational gap in the evaluation of drug-induced QT c interval prolongation

Chain, Anne S.Y., Dubois, Vincent F.S., Danhof, Meindert, Sturkenboom, Miriam C.J.M., Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 2.41 MB

english, 2013

5

A model-based approach to treatment comparison in acute migraine

Hugo J. Maas, Meindert Danhof, Oscar Della Pasqua

Journal:

British Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 310 KB

english, 2006

6

The impact of composite AUC estimates on the prediction of systemic exposure in toxicology experiments

Sahota, Tarjinder, Danhof, Meindert, Della Pasqua, Oscar

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

7

Non-inferiority double-blind randomised controlled trial comparing gabapentin versus tramadol for the treatment of chronic neuropathic or mixed pain in children and adolescents: the GABA-1 trial—a study protocol

Kaguelidou, Florentia, Le Roux, Enora, Mangiarini, Laura, Lundin, Rebecca, de Leeuw, Thomas G, Della Pasqua, Oscar, Felisi, Mariagrazia, Bonifazi, Donato, Tibboel, Dick, Ceci, Adriana, de Wildt, Saski

Journal:

Year:

2019

Language:

english

File:

PDF, 392 KB

english, 2019

8

Population pharmacokinetic–pharmacodynamic modelling of S 15535, a 5-HT1A receptor agonist, using a behavioural model in rats

Peter Vis, Oscar Della Pasqua, Menno Kruk, Delphine Martin, Elisabeth Mocaër, Meindert Danhof, Roeline Jochemsen

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 167 KB

english, 2001

9

Population pharmacokinetics of NNZ-2566 in healthy subjects

Oosterholt, Sean P., Horrigan, Joseph, Jones, Nancy, Glass, Larry, Pasqua, Oscar Della

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

10

Effect of raxibacumab on immunogenicity of Anthrax Vaccine Adsorbed: a phase 4, open-label, parallel-group, randomised non-inferiority study

Skoura, Nancy, Wang-Jairaj, Jie, Della Pasqua, Oscar, Chandrasekaran, Vijayalakshmi, Billiard, Julia, Yeakey, Anne, Smith, William, Steel, Helen, Tan, Lionel K

Journal:

The Lancet Infectious Diseases

Year:

2020

File:

PDF, 369 KB

2020

11

Analysis of responses in migraine modelling using hidden Markov models

Vladimir V. Anisimov, Hugo J. Maas, Meindert Danhof, Oscar Della Pasqua

Journal:

Statistics in Medicine

Year:

2007

Language:

english

File:

PDF, 179 KB

english, 2007

12

Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy

Gijs Santen, Roberto Gomeni, Meindert Danhof, Oscar Della Pasqua

Journal:

Journal of Psychiatric Research

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

13

How long will treatment guidelines for TB continue to overlook variability in drug exposure?

Muliaditan, Morris, Della Pasqua, Oscar

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2019

Language:

english

File:

PDF, 496 KB

english, 2019

14

Mimicking in-vivo exposures to drug combinations in-vitro: anti-tuberculosis drugs in lung lesions and the hollow fiber model of infection

Kloprogge, Frank, Hammond, Robert, Kipper, Karin, Gillespie, Stephen H., Della Pasqua, Oscar

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.98 MB

english, 2019

15

Integrative knowledge management to enhance pharmaceutical R&D

Marti-Solano, Maria, Birney, Ewan, Bril, Antoine, Pasqua, Oscar Della, Kitano, Hiroaki, Mons, Barend, Xenarios, Ioannis, Sanz, Ferran

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 587 KB

english, 2014

16

Modelâbased metaâanalysis of the time to first acute urinary retention or BPHârelated surgery in patients with moderate or severe symptoms

D'Agate, Salvatore, Chavan, Chandrashekhar, Manyak, Michael, PalaciosâMoreno, Juan Manuel, Oelke, Matthias, Michel, Martin C., Roehrborn, Claus G., Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2020

File:

PDF, 2.37 MB

2020

17

Not-in-trial simulation I: Bridging cardiovascular risk from clinical trials to real-life conditions

Chain, Anne S. Y., Dieleman, Jeanne P., van Noord, Charlotte, Hofman, Albert, Stricker, Bruno H. Ch., Danhof, Meindert, Sturkenboom, Miriam C. J. M., Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 969 KB

english, 2013

18

Correction to: Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials

van Dijkman, Sven C., de Jager, Nico C. B., Rauwé, Willem M., Danhof, Meindert, Della Pasqua, Oscar

Journal:

Clinical Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 362 KB

english, 2018

19

Integration of Pharmacogenetics and Pharmacogenomics in Drug Development: Implications for Regulatory and Medical Decision Making in Pediatric Diseases

Piana, Chiara, Surh, Linda, Furst-Recktenwald, Sabine, Iolascon, Achille, Jacqz-Aigrain, Evelyne M., Jonker, Ineke, Russo, Roberta, van Schaik, Ron H.N., Wessels, Judith, Della Pasqua, Oscar E.

Journal:

Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 171 KB

english, 2012

20

Covariate effects and population pharmacokinetics of lamivudine in HIV-infected children

Piana, Chiara, Zhao, Wei, Adkison, Kimberly, Burger, David, Jacqz-Aigrain, Evelyne, Danhof, Meindert, Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

21

Implications of pharmacogenetics for the therapeutic use of antiepileptic drugs

Piana, Chiara, Antunes, Natalicia de Jesus, Della Pasqua, Oscar

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2014

Language:

english

File:

PDF, 755 KB

english, 2014

22

Influence of verapamil on the pharmacokinetics of oxcarbazepine and of the enantiomers of its 10-hydroxy metabolite in healthy volunteers

de Jesus Antunes, Natalícia, Wichert-Ana, Lauro, Coelho, Eduardo Barbosa, Della Pasqua, Oscar, Alexandre Junior, Veriano, Takayanagui, Osvaldo Massaiti, Tozatto, Eduardo, Marques, Maria Paula, Lanchot

Journal:

European Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 529 KB

english, 2016

23

Pharmacotherapy in pediatric epilepsy: from trial and error to rational drug and dose selection – a long way to go

van Dijkman, Sven C., Alvarez-Jimenez, Ricardo, Danhof, Meindert, Della Pasqua, Oscar

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

24

Correlation between in vitro and in vivo concentration–effect relationships of naproxen in rats and healthy volunteers

Dymphy R H Huntjens, David J M Spalding, Meindert Danhof, Oscar E Della Pasqua

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 199 KB

english, 2006

25

Efficacy of pulmonary insulin delivery in diabetic rats: Use of a model-based approach in the evaluation of insulin powder formulations

Maryam Amidi, Kevin M. Krudys, Cor J. Snel, Daan J.A. Crommelin, Oscar E. Della Pasqua, Wim E. Hennink, Wim Jiskoot

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 1.39 MB

english, 2008

26

Biomarker exposure-response relationships as the basis for rational dose selection: Lessons from a simulation exercise using a selective COX-2 inhibitor

Taneja, Amit, Oosterholt, Sean P., Danhof, Meindert, Della Pasqua, Oscar

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 6.89 MB

english, 2016

27

MID3: Mission Impossible or Model‐Informed Drug Discovery and Development? Point‐Counterpoint Discussions on Key Challenges

Krishnaswami, Sriram, Austin, Daren, Della Pasqua, Oscar, Gastonguay, Marc R., Gobburu, Jogarao, van der Graaf, Piet H., Ouellet, Daniele, Tannenbaum, Stacey, Visser, Sandra A.G.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2020

Language:

english

File:

PDF, 790 KB

english, 2020

28

Compartmental Modeling of Transdermal Iontophoretic Transport II:In VivoModel Derivation and Application

Akhmad Kharis Nugroho, Oscar Della-Pasqua, Meindert Danhof, Joke A. Bouwstra

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 497 KB

english, 2005

29

Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model

Gijs Santen, Meindert Danhof, Oscar Della Pasqua

Journal:

Journal of Psychiatric Research

Year:

2008

Language:

english

File:

PDF, 273 KB

english, 2008

30

Sensitivity of the Montgomery Asberg Depression Rating Scale to response and its consequences for the assessment of efficacy

Gijs Santen, Meindert Danhof, Oscar Della Pasqua

Journal:

Journal of Psychiatric Research

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

31

Translational pharmacology: from animal to man and back

Della Pasqua, Oscar

Journal:

Drug Discovery Today: Technologies

Year:

2013

Language:

english

File:

PDF, 218 KB

english, 2013

32

Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations

Clinckers, Ralph, Smolders, Ilse, Vermoesen, Katia, Michotte, Yvette, Danhof, Meindert, Voskuyl, Rob, Della Pasqua, Oscar

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2009

Language:

english

File:

PDF, 407 KB

english, 2009

33

Characterizing QT interval prolongation in early clinical development: a case study with methadone

Dubois, Vincent F. S., Danhof, Meindert, Della Pasqua, Oscar

Journal:

Pharmacology Research & Perspectives

Year:

2017

Language:

english

File:

PDF, 3.30 MB

english, 2017

34

Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors

Dymphy R.H. Huntjens, David J.M. Spalding, Meindert Danhof, Oscar E. Della Pasqua

Journal:

European Journal of Pain

Year:

2009

Language:

english

File:

PDF, 602 KB

english, 2009

35

The pharmacokinetics and pharmacological effect of (S)-5-OH-DPAT following controlled delivery with transdermal iontophoresis

Oliver W. Ackaert, Jeroen De Graan, Shanna Shi, Rob Vreeken, Oscar E. Della Pasqua, Durk Dijkstra, Ben H. Westerink, Meindert Danhof, Joke A. Bouwstra

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 820 KB

english, 2011

36

Value of probabilistic concentration–response modeling in cardiac safety

Kevin Krudys, Oscar Della-Pasqua, Bronagh Heath, Bela Patel, Nick McMahon

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

37

Fit-for-purpose pharmacogenomic biomarkers in drug development: a project team case study with ‘what-ifs’

Surh, Linda C, Lesko, Lawrence J, Hobbs, Stuart, Gutman, Steve, Minasian, Lori M, Pasqua, Oscar E Della, Austin, MJ Finley, Lu, Kan

Journal:

Pharmacogenomics

Year:

2009

Language:

english

File:

PDF, 469 KB

english, 2009

38

Evaluation of pharmacokineticâpharmacodynamic relationships and selection of drug combinations for tuberculosis

Muliaditan, Morris, Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2020

File:

PDF, 1.93 MB

2020

39

Population pharmacokinetics of abacavir in infants, toddlers and children

Zhao, Wei, Piana, Chiara, Danhof, Meindert, Burger, David, Della Pasqua, Oscar, Jacqz-Aigrain, Evelyne

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

40

Impact of early vs. delayed initiation of dutasteride/tamsulosin combination therapy on the risk of acute urinary retention or BPH-related surgery in LUTS/BPH patients with moderate-to-severe symptoms at risk of disease progression

DâAgate, Salvatore, Chavan, Chandrashekhar, Manyak, Michael, Palacios-Moreno, Juan Manuel, Oelke, Matthias, Michel, Martin C., Roehrborn, Claus G., Della Pasqua, Oscar

Journal:

World Journal of Urology

Year:

2020

File:

PDF, 3.44 MB

2020

41

Integration of PKPD relationships into benefit-risk analysis

Bellanti, Francesco, van Wijk, Rob C., Danhof, Meindert, Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

42

Ethambutol disposition in humans: Challenges and limitations of whole-body physiologically-based pharmacokinetic modelling in early drug development

Carrara, Letizia, Magni, Paolo, Teutonico, Donato, Pasotti, Lorenzo, Della Pasqua, Oscar, Kloprogge, Frank

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 3.19 MB

2020

43

Pharmacokinetics and pharmacodynamics analysis of transdermal iontophoresis of 5-OH-DPAT in rats: In vitro–in vivo correlation

Akhmad Kharis Nugroho, Stefan G. Romeijn, Raphaël Zwier, Jan B. de Vries, Durk Dijkstra, Håkan Wikström, Oscar Della-Pasqua, Meindert Danhof, Joke A. Bouwstra

Journal:

Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 462 KB

english, 2006

44

Population pharmacokinetics and maximum a posteriori probability Bayesian estimator of abacavir: application of individualized therapy in HIV-infected infants and toddlers

Wei Zhao, Massimo Cella, Oscar Della Pasqua, David Burger, Evelyne Jacqz-Aigrain, on behalf of Pediatric European Network for Treatment of AIDS (PENTA) 15 study group

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

45

Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research

Meindert Danhof, Elizabeth C.M. de Lange, Oscar E. Della Pasqua, Bart A. Ploeger, Rob A. Voskuyl

Journal:

Trends in Pharmacological Sciences

Year:

2008

Language:

english

File:

PDF, 368 KB

english, 2008

46

Analysis of Oxcarbazepine and the 10-Hydroxycarbazepine Enantiomers in Plasma by LC-MS/MS: Application in a Pharmacokinetic Study

de Jesus Antunes, Natalicia, Wichert-Ana, Lauro, Coelho, Eduardo Barbosa, Della Pasqua, Oscar, Alexandre, Veriano, Takayanagui, Osvaldo Massaiti, Tozatto, Eduardo, Lanchote, Vera Lucia

Journal:

Year:

2013

Language:

english

File:

PDF, 368 KB

english, 2013

47

Model-based evaluation of drug-induced QTc prolongation for compounds in early development

Dubois, Vincent F. S., Yu, Huixin, Danhof, Meindert, Della Pasqua, Oscar

Journal:

British Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 3.69 MB

english, 2015

48

Modelling of the outcome of non-inferiority trials by integration of historical data

Alberto Russu, Erik van Zwet, Giuseppe De Nicolao, Oscar Della Pasqua

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2011

Language:

english

File:

PDF, 1.84 MB

english, 2011

49

Compartmental Modeling of Transdermal Iontophoretic Transport: I.In VitroModel Derivation and Application

Akhmad Kharis Nugroho, Oscar Della Pasqua, Meindert Danhof, Joke A. Bouwstra

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 368 KB

english, 2004

50

Translation of drug effects from experimental models of neuropathic pain and analgesia to humans

Amit Taneja, Vincenzo Luca Di Iorio, Meindert Danhof, Oscar Della Pasqua

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

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